Niedokrwistości ze szczególnym uwzględnieniem anemii immunohemolitycznych – cz. I. Ostre przypadki hematologiczne od diagnozy do leczenia – na podstawie przypadków klinicznych

Reticulocyte Counts

Raw (uncorrected) manual reticulocyte counts can be misleading when moderate to severe anemia is present because reticulocytes are quantified as a percentage of the total number of erythrocytes (reticulocytes plus mature erythrocytes) counted. The raw reticulocyte count (percent) would be higher in an anemic animal (with a lower number of mature erythrocytes) than it would be in a normal animal (with a higher number of mature erythrocytes), even if the actual numbers of reticulocytes per microliter in the circulation were the same in each animal.

If the total RBC count is known, an absolute reticulocyte count (reticulocytes per microliter) can be determined. This is done by multiplying the percentage of reticulocytes counted (expressed as a fraction) by the total RBC count.

Absolute reticulocyte count = RBC count (per microliter) X raw reticulocyte count (fraction).

Absolute reticulocyte counts in normal dog are generally less than 80 x 10³/μL when manual counts are done., Absolute aggregated reticulocyte counts in normal cats range between 0 and 95 x 10³/μL and absolute punctate reticulocyte counts between 0 and 650 x 10³/μL. Absolute reticulocyte counts can also be determined directly by flow cytometry with some automated hematology analyzers.

Anemias resulting from decreased erythrocyte production

Anemia resulting from decreased erythrocyte production lacks evidence [...]

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