Immunomodulacja: leczenie żywieniem – cz. II

Nutrition interacts with the immune system at multiple levels

Nutrition and the immune system interact at multiple levels and for simplicity it can be considered in a framework of four stages. Stages I & II are passive because they involve providing the immune system with essential nutrients. Stages III & IV focus on modifying the immune response using agents such as IRMs that primarily target the PAMP receptors in the gut and involve more active approaches in enhancing the immune status.

Stage I: Complete nutrition

At the primary level the focus revolves around dietary energy, protein, vitamins (vitamin A, C and E) and minerals such as Zn, Mg, Fe etc (described in detail in Diet and Human Immune Function, 2003, Humana Press). Minerals such as Ca+ and Mg+ drive signaling mechanisms in the immune system and are therefore also important for enhanced immune response. Providing basic nutrition is the very least that we can do for the immune system.

Stage II: Optimizing macro & micro nutrients

The second stage involves the optimization of key nutrients that are critical for the immune cells. The immune system has a need for certain nutrients and providing greater amounts of these key nutrients would target the immune cells better. A temporary deficiency of a key nutrient can negatively [...]

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