Niedokrwistości ze szczególnym uwzględnieniem anemii immunohemolitycznych – cz. I. Ostre przypadki hematologiczne od diagnozy do leczenia – na podstawie przypadków klinicznych
Mean Cell Hemoglobin Concentration
The MCHC represents the average hemoglobin concentration within erythrocytes. To calculate MCHC one must divide the hemoglobin concentration in whole blood (in grams per deciliter) by the HCT (as a percentage), and multiply that value by 100.
High MCHC values are artifacts. They may result from in vivo or in vitro hemolysis, lipemia, or presence of Heinz bodies within erythrocytes.
If hemolysis occurs, some hemoglobin is free in plasma; but the formula used to calculate the MCHC assumes that all measured hemoglobin is contained within erythrocytes. High MCHC may also occur if there is agglutination of erythrocytes. The MCHC is low in iron deficiency because there is inadequate iron to support the synthesis of normal amounts of hemoglobin (4).
Red Cell Distribution Width
The red cell distribution width (RDW) is an electronic measure of anisocytosis or erythrocyte volume heterogeneity.
A histogram of the volume of individual erythrocytes reveals a plot approximating a Gaussian distribution. RDW will be increased in cases where the degree of anisocytosis (as estimated on the stained blood film) is increased. It is often increased in regenerative anemias because reticulocytes and young erythrocytes are larger than mature erythrocytes.
Like the MCV, the number of large erythrocytes [...]
którzy są subskrybentami naszego portalu.
i ciesz się dostępem do bazy merytorycznej wiedzy!
POSTĘPOWANIA
w weterynarii
