Niedokrwistości ze szczególnym uwzględnieniem anemii immunohemolitycznych – cz. I. Ostre przypadki hematologiczne od diagnozy do leczenia – na podstawie przypadków klinicznych
Morphology of red cells
Erythrocyte morphology should be examined and recorded as either normal or abnormal. Erythrocytes on blood films from normal cats often exhibit rouleaux formation and may contain a low percentage of small, spherical nuclear remnants called Howell-Jolly bodies. However, rouleaux and the presence of Howell-Jolly bodies should be recorded on the hematology form when they appear in blood films from dogs.
Additional observations regarding erythrocyte morphology, such as the degree of polychromasia (presence of polychromatophilic erythrocytes), anisocytosis (variation in size), and poikilocytosis (abnormal shape) should also be made.
Polychromatophilic erythrocytes are reticulocytes that stain bluish-red because of combined presence of hemoglobin (red-staining) and ribosomes (blue-staining).
Abnormal erythrocyte shapes should be classified as specifically as possible, because specific shape abnormalities can aid in determining the nature of a disorder that may be present. Examples of abnormal erythrocyte morphology include echinocytes, acanthocytes, schistocytes, keratocytes, dacryocytes, elliptocytes, eccentrocytes, and spherocytes.
Rouleaux formation
Rouleaux formation depends on the nature of the erythrocytes, the composition of plasma, and on the presence of high-molecular weight proteins in plasma. Increased concentrations of globulin proteins – including fibrinogen, haptoglobin, and immunoglobulins – potentiate rouleaux formation in association with inflammatory conditions. Rouleaux formation can also occur in association with some lymphoproliferative disorders in which one [...]
którzy są subskrybentami naszego portalu.
i ciesz się dostępem do bazy merytorycznej wiedzy!
POSTĘPOWANIA
w weterynarii
